Fig. 3From: Human iPS cell-derived mural cells as an in vitro model of hereditary cerebral small vessel diseaseImmunoreactivity of components of granular osmiophilic materials. a Representative images of N3ECD staining. Integrated density (IntDen) of N3ECD immunoreactivity (IR) was significantly increased in CADASIL MCs (n = 3) than controls (n = 4). b Some of N3ECD deposits in CADASIL MCs were positive for LTBP-1 and HtrA1 (arrows). Bars represent 10 μm. *** p < 0.0001Back to article page