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Fig. 4 | Molecular Brain

Fig. 4

From: Human iPS cell-derived mural cells as an in vitro model of hereditary cerebral small vessel disease

Fig. 4

Functional differences of CADASIL MCs (n = 3) compared to controls (n = 4). a The proliferation was assessed by a WST-8 assay daily for 4 days; no significant difference was found. b Collagen contraction assay showed no significant difference in contraction between controls and CADASIL. c Cell migration, as evaluated by the scratch assay, was significantly increased in CADASIL iPSMCs, which was also evident from the activated actin metabolism as indicated by the increased G−/F- actin ratio (d). The error bars represent the SEM. *p < 0.05

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