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Fig. 3 | Molecular Brain

Fig. 3

From: Role of lateral amygdala calstabin2 in regulation of fear memory

Fig. 3

Genetic knockout (KO) calstabin2 disrupts long-term potentiation (LTP) induction both in cortical and thalamic inputs to the lateral amygdala (LA). a A schematic representation showing the experiment design in which 100 stimuli at 2 Hz were delivered to either cortical or thalamic afferents to the LA and LA neurons were held at + 30 mV. Sti and Rec indicate the location of stimulation and recording electrodes, respectively. b, c LTP in cortical (b) and thalamic (c) inputs to the LA from wild-type (WT) and KO mice. Insets represent excitatory postsynaptic currents (EPSCs) before (1) and after (2) LTP induction. d Summary plots of the data in b and c. Data were analyzed with independent Student’s t-test. *p < 0.05 and ***p < 0.001

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