Fig. 2
The expression levels of miR-326 and DOR in cortical tissues of neonatal rats with HIBD. (a) The HIBD rat model was verified by TTC staining. There were obvious white infarctions in the left cerebral cortex in the HI group, while the right cerebral cortex under HI and both sides of the control group did not show any infarction areas. (b) The expression levels of miR-326 did not change immediately at 0 h after HI (nP > 0.05) and significantly decreased at 24 h, 48 h and 72 h after HI injury in neonatal rats (**P < 0.01; ***P < 0.005). (c) The mRNA expression levels of DOR were greatly upregulated at 24 h and 48 h after HI injury (*P < 0.05; ****P < 0.001) but were significantly downregulated 72 h after HI injury (****P < 0.001). The protein expression levels of DOR were consistent with the mRNA expression levels