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Fig. 1 | Molecular Brain

Fig. 1

From: Cortical potentiation induced by calcitonin gene-related peptide (CGRP) in the insular cortex of adult mice

Fig. 1

CGRP (10 nM) enhanced excitatory synaptic transmission in the IC. a Schematic diagram (left) and representative recording diagram (right) showed the placement of stimulating and recording electrodes in the IC. b Top: sample traces of EPSCs with single-pulse stimulation during the baseline, the application of CGRP and washout period. Bottom: a time course plot of a representative single example. c The averaged data showed the amplitude significantly increased during the application of CGRP (10 nM) and washout period when compared with baseline. The 1 nM CGRP were used as a control, indicating the dose-dependent characteristic of the effect of CGRP (n = 9 neurons/6 mice for 10 nM CGRP, filled circles; n = 6 neurons/4 mice for 1 nM CGRP, open circles)

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