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Fig. 4 | Molecular Brain

Fig. 4

From: Cortical potentiation induced by calcitonin gene-related peptide (CGRP) in the insular cortex of adult mice

Fig. 4

CGRP altered paired-pulse ratio in the IC. a Left: a time line plot of one representative sample. Right: sample traces of this neuron. b The time courses plot (left) and histograms (right) for the pooled data illustrated that PPR significantly decreased during the application of CGRP (10 nM) and washout period when compared with baseline (n = 9 neurons/6 mice). c CGRP1 receptor antagonist CGRP8–37 (left) and non-peptide CGRP1 receptor antagonist BIBN 4096 (right) blocked the decrease of PPR after applied CGRP (CGRP8–37, n = 7 neurons/5 mice; BIBN 4096, n = 8 neurons/4 mice). **p < 0.01 compared with baseline, error bars indicated SEM

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