Fig. 5

Survival rate of WT-VSV and Mutant-VSV infected mice. WT-VSV, Mutant-VSV and PBS were injected intracranially into the DG domain of adult mice. WT-VSV was rapidly lethal within 1 week and more than half of all deaths occured at 4 DPI, which occured at 14 DPI in Mutant-VSV group. The percent survival was analyzed by Log-rank test (n = 10 in each group; P < 0.0001). *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001