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Table 2 The detailed information of top 20 up-regulated and top 20 down-regulated mRNAs

From: Transcriptomic analysis of long noncoding RNAs and mRNAs expression profiles in the spinal cord of bone cancer pain rats

gene name

description

log2FC

P value

Up-regulated

 RT1-Ba

RT1 class II, locus Ba

6.81

0

 Cd74

Cd74 molecule, major histocompatibility complex, class II invariant chain

6.23

0

 RT1-Bb

RT1 class II, locus Bb

6.82

0

 RT1-Da

RT1 class II, locus Da

6.79

0

 Cxcl13

chemokine (C-X-C motif) ligand 13

8.98

3.55E-254

 RT1-Db1

RT1 class II, locus Db1

4.74

1.35E-232

 Itgax

integrin, alpha X

6.15

3.62E-200

 C3

complement component 3

2.98

2.94E-196

 Ciita

class II, major histocompatibility complex, transactivator

8.39

2.44E-191

 Ncf1

neutrophil cytosolic factor 1

3.65

8.10E-173

 Lyz2

lysozyme 2

3.92

1.48E-161

 Cxcl16

chemokine (C-X-C motif) ligand 16

3.88

1.53E-160

 Clec7a

C-type lectin domain family 7 member A transcript variant 1; Dectin-1; Protein Clec7a

6.85

4.13E-156

 Irf8

interferon regulatory factor 8

3.01

7.18E-139

 Scin

scinderin

> 10

7.22E-137

 Cxcl9

chemokine (C-X-C motif) ligand 9

5.75

5.15E-135

 Plek

pleckstrin

3.04

5.72E-132

 Ubd

ubiquitin D

6.71

3.27E-131

 Ptprc

protein tyrosine phosphatase, receptor type, C

3.46

4.64E-123

 Gpnmb

glycoprotein (transmembrane) nmb

2.88

5.98E-123

Down-regulated

 AABR07031184.1

–

−7.84

2.04E-12

 Crlf1

cytokine receptor-like factor 1

−1.10

6.20E-11

 Hspa1b

heat shock protein 1B

−1.17

3.59E-07

 Tnnc2

troponin C type 2 (fast)

−1.26

6.34E-06

 F12

coagulation factor XII (Hageman factor)

−3.45

6.14E-05

 Mesp2

mesoderm posterior basic helix-loop-helix transcription factor 2

−1.74

6.18E-05

 Hif3a

hypoxia inducible factor 3, alpha subunit

−1.25

0.000125375

 Hpn

hepsin

−1.25

0.000186518

 Agtr1a

angiotensin II receptor, type 1a

−1.01

0.000198987

 Slc7a15

solute carrier family 7 (cationic amino acid transporter, y + system), member 15

−3.25

0.000249069

 Ascl2

achaete-scute family bHLH transcription factor 2

−1.81

0.00045278

 Cdc42ep2

CDC42 effector protein (Rho GTPase binding) 2

−1.15

0.000468742

 Alb

albumin

−1.47

0.000614844

 Cfap46

cilia and flagella associated protein 46

−1.46

0.000737338

 AC096430.2

–

−1.19

0.000745128

 AABR07069524.1

–

−2.02

0.00105327

 Ripply2

ripply transcriptional repressor 2

−1.22

0.001084151

 Ucn

urocortin

<−10

0.001361414

 Eln

elastin

−1.31

0.00150543

 7SK

7SK RNA

−2.66

0.001521089