Fig. 1
From: Physical activity reduces anxiety and regulates brain fatty acid synthesis
Characterization of the running mouse model and experimental timeline. (a) Distance traveled by mice provided with running wheels for up to 36 days. Data are mean +/- S.D; n=14. The graph includes also the timeline of experiments. Vertical arrows indicate BrdU injections, evaluation of metabolome and neurogenesis, behavioral testing, and cell proliferation in the dentate gyrus (DG). Weight gain (b), food consumption (c), water intake (d), blood creatinine (e) and triglyceride levels (f) determined during the entire running and/or inactive period (n=6-12). (g) Doublecortin (DCX, a neuronal differentiation marker) protein expression in the hippocampus of the running and inactive mice as determined by immunoblotting. Upper graph, representative images, lower graph, quantitative data normalized to β-III-tubulin levels (a housekeeping protein). (h) BrdU-positive cells in the hippocampus of the running and inactive mice. (b-h) graphs represent median with min. - max.; *p < 0.05, ***p < 0.001.