Fig. 3
From: Activity-dependent redistribution of CaMKII in the postsynaptic compartment of hippocampal neurons
Representative images of five types of CaMKII distribution pattern at the PSD. Electron micrographs of dissociated hippocampal cultures immunogold labeled with an antibody against α-CaMKII. The percentages of each type present in different experimental conditions are listed in the right column (data from Additional Files 1 and 2). In Type I (a, b), label was absent in both the PSD core and pallium, and only present in the nearby cytoplasm. In Type II (c, d), Label was evenly distributed in the PSD and cytoplasm. In Type III (e, f), label was preferentially localized in the PSD core. In Type IV (g, h), Label was preferentially in the PSD pallium. In Type V (i, j), label was concentrated at the PSD, confined within the distal border of the pallium. Samples were under low calcium conditions (a and c, EGTA), control conditions (b, d, e, f, g, h, Ringer treatment), and stimulated conditions (i, high K+; and j, NMDA). Scale bar = 100 nm