Exome sequencing study revealed novel susceptibility loci in subarachnoid hemorrhage (SAH)

Table 2 Candidate genes in SAH identified by burden test of rare variants

Gene	Number of Cases with mutations	Number of Controls with mutations	Number of Cases without mutations	Number of Controls without mutations	P value	OR
OBSCN	26	11	68	82	0.005	2.834
ABCG8	7	0	87	93	0.007	Inf
PIGG	7	0	87	93	0.007	Inf
GOLGA2	6	0	88	93	0.015	Inf
MTMR4	6	0	88	93	0.015	Inf
MYH1	6	0	88	93	0.015	Inf
OTOGL	6	0	88	93	0.015	Inf
TCF3	6	0	88	93	0.015	Inf
TJP1	10	2	84	91	0.017	5.374
KMT2C	8	1	86	92	0.018	8.482
ADGRV1	16	6	78	87	0.021	2.958
FBN3	9	2	85	91	0.030	4.782
ABCG5	5	0	89	93	0.030	Inf
BCL9	5	0	89	93	0.030	Inf
C1orf94	5	0	89	93	0.030	Inf
CEBPZ	5	0	89	93	0.030	Inf
COG3	5	0	89	93	0.030	Inf
CTC1	5	0	89	93	0.030	Inf
FDXR	5	0	89	93	0.030	Inf
GRIK3	5	0	89	93	0.030	Inf
INCENP	5	0	89	93	0.030	Inf
IQGAP3	5	0	89	93	0.030	Inf
KNDC1	5	0	89	93	0.030	Inf
LETMD1	5	0	89	93	0.030	Inf
METTL22	5	0	89	93	0.030	Inf
NCOA6	5	0	89	93	0.030	Inf
PDZD7	5	0	89	93	0.030	Inf
PIF1	5	0	89	93	0.030	Inf
PLXNA4	5	0	89	93	0.030	Inf
RAPGEFL1	5	0	89	93	0.030	Inf
RGS14	5	0	89	93	0.030	Inf
SCN7A	5	0	89	93	0.030	Inf
THEG	5	0	89	93	0.030	Inf
VEPH1	5	0	89	93	0.030	Inf
ZFP90	5	0	89	93	0.030	Inf
LENG8	7	1	87	92	0.033	7.339
NIPBL	7	1	87	92	0.033	7.339
TECPR2	7	1	87	92	0.033	7.339

ISSN: 1756-6606