Fig. 7
From: Drp1 is widely, yet heterogeneously, distributed in the mouse central nervous system
Colabeling of Drp1 and GAD67. a. The heterogeneous distribution of Drp1 in different kinds of neurons was further observed. GAD67-GFP transgenic mice were used to observe the colabeling of GABAergic neurons and Drp1 in different brain regions. b. Drp1 and GAD67 were double-labeled in SIMpu. The pu cells expressed Drp1 and GAD67, demonstrating complete colabeling. c. Drp1 and GAD67 in the medulla. Drp1 was highly expressed in SPVI and weakly expressed in MDRNd, while GAD67 showed lower expression in SPVI and higher expression in MDRNd. d. Drp1 and GAD67 in ECU. The results showed that Drp1 and GAD67 were not colabeled in most of this area. Bar = 100 μm (A-C); 25 μm (A1-C1). Abbreviations: GAD67: glutamic acid decarboxylase 67; GABA: γ-Aminobutyric acid; SIMpu: simple lobule, Purkinje layer; SIMmo: simple lobule, molecular layer; SIMgr: simple lobule, granular layer; MDRNd: medullary reticular nucleus, dorsal part; SPVI: spinal nucleus of the trigeminal, interpolar part; ECU: external cuneate nucleus; NTS: nucleus of solitary tract; PAS: parasolitary nucleus