Drp1 is widely, yet heterogeneously, distributed in the mouse central nervous system

Table 2 Value of Drp1 fluorescence intensity in different glioma grades

	Control	grade I	grade II	grade III	grade IV
1	0.49	0.134	0.273	0.326	0.254
2	0.433	0.232	0.362	0.618	0.273
3	0.538	0.454	0.267	0.9	0.364
4	0.54	0.314	0.539	0.556	0.508
5	0.45	0.18	0.773	0.585	0.67
6	0.269	0.19	0.245	0.252	0.332
7	0.513	0.173	0.381	0.657	0.339
8	0.335	0.234	0.402	1.139	0.316
Mean value	0.446	0.239	0.405	0.629	0.382

Eight fluorescent spots were randomly selected in every grade. Value of Drp1 fluorescence intensity was calculated by ImageJ software. One-way ANOVA was used for statistical analysis Results showed that Drp1 expression was significantly different in glioma I-IV grade (p = 0.01). After LSD test, Drp1 expression in control group was higher than that in grade I (p = 0.018). On the contrary, grade III was higher than that in control group (p = 0.036), grade I (p < 0.001), grade II (p = 0.011), and grade IV (p = 0.001)

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