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Fig. 4 | Molecular Brain

Fig. 4

From: Characterization of a pathogenic variant in GBA for Parkinson’s disease with mild cognitive impairment patients

Fig. 4

The rs12411216 SNP affects the aggregation of p-α-syn. K-DHS: DHS-knockout cells; T-SNP: SNP-replaced cells. Blue fluorescence represents 4′,6-diamidino-2-phenylindole (DAPI)-stained nuclei, and green fluorescence represents p-α-Syn expression. Immunofluorescence experiments indicated that rs12411216 affected p-α-Syn aggregation. ***p < 0.001. Data are expressed as means ± SEMs

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