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Fig. 4 | Molecular Brain

Fig. 4

From: Region-specific astrogliosis: differential vessel formation contributes to different patterns of astrogliosis in the cortex and striatum

Fig. 4

Cell proliferation is not different between the injured cortex and striatum. a, b Upper panel: Sections obtained from the intact and or 3 d post injury were stained with antibodies for Ki67 (a) and GFAP and Ki67 (b). Ki67/GFAP double-positive cells (arrows) and Ki67-positive/GFAP-negative cells (arrowheads) were found in the P1 region and damage core. Dotted lines in (b), edges of damage areas. Lower panel: For quantification of astrocyte proliferation, sections were stained with antibodies for Ki67 and GFAP. With Imaris software, the number of Ki67/GFAP double-positive cells and Ki67-positive/GFAP-negative cells were analyzed in 4 (cortex) or 6 mice (striatum), and 3 sections from each mouse. Values are means ± SEMs. ns, not significant; **, p < 0.001; one-way ANOVA, F (3, 25)=0.8549, p = 0.4773 (a); Student’s t-test, F (3, 5)=2.766, p = 0.1571 (b)

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Molecular Brain

ISSN: 1756-6606