Fig. 2

HDAC6 is required for the Golgi polarization into a major dendrite. a The Golgi apparatus was stained by GM130 antibody (red). Hippocampal neurons expressing HDAC6 shRNA did not polarize the Golgi into a dendrite. Expression of HDAC6 shRNA together with shRNA resistant HDAC6 polarized the Golgi into a dendrite. Scale bar, 50 μm. b Quantification of the percentage of neurons with dendritic Golgi. Data represents average of three independent experiments (n = 90–120 for each group in each experiment). **p < 0.01, ***p < 0.001 by two-tailed Student’s t-test. Error bar means ± S.E.M. in all graphs