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Fig. 3 | Molecular Brain

Fig. 3

From: Cortico-amygdala interaction determines the insular cortical neurons involved in taste memory retrieval

Fig. 3

Functional connectivity between the IC and BLA is increased in stronger US conditioning. a Experimental schema. b Data showing the aversion index in the memory retrieval test (Stronger US, N = 14; Weaker US, N = 14; No US, N = 13). c Left panels show schema of representative coronal sections at each AP position (AP = + 1.0 mm; IC, AP = − 1.7 mm; BLA, AP = + 1.8 mm; PrL). Analyzed areas are depicted by a red line. Representative images showing c-fos (magenta) after memory retrieval test. Scale bar = 100 μm. d-f Probability of expression of c-fos in DAPI+ cells in the IC (d), BLA (e) and PrL (f) (N = 5 in each group). g-i Probabilities of occurrence of c-fos + neurons in the IC versus BLA (g), BLA versus PrL (h), and IC versus PrL (i) are plotted for each mouse. The r represents correlation coefficient. Data are represented as mean ± SEM; *p < 0.05 and ***p < 0.001 (Stronger US, red columns and circles; Weaker US group, blue columns and triangles)

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