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Fig. 3 | Molecular Brain

Fig. 3

From: Conditional knockout of leptin receptor in neural stem cells leads to obesity in mice and affects neuronal differentiation in the hypothalamus early after birth

Fig. 3

The level of activated pSTAT3 stimulated by leptin markedly decreased in all subregions of the hypothalamus of Nes-cKO mice compared with control littermates. a-f Representative images showing leptin-activated pSTAT3 and NeuN expression in the indicated subregions of the hypothalamus of Nes-cKO mice and control littermates. Scale bars, 100 μm. g Quantification of the ratio of pSTAT3 + NeuN+ cells to total NeuN+ cells (n = 4 mice for each genotype). ***p < 0.001; Student’s two-tailed, unpaired t-test. Error bars indicate s.e.m.

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