Fig. 3From: Conditional knockout of leptin receptor in neural stem cells leads to obesity in mice and affects neuronal differentiation in the hypothalamus early after birthThe level of activated pSTAT3 stimulated by leptin markedly decreased in all subregions of the hypothalamus of Nes-cKO mice compared with control littermates. a-f Representative images showing leptin-activated pSTAT3 and NeuN expression in the indicated subregions of the hypothalamus of Nes-cKO mice and control littermates. Scale bars, 100 μm. g Quantification of the ratio of pSTAT3 + NeuN+ cells to total NeuN+ cells (n = 4 mice for each genotype). ***p < 0.001; Student’s two-tailed, unpaired t-test. Error bars indicate s.e.m.Back to article page