Fig. 4From: Altered dopaminergic pathways and therapeutic effects of intranasal dopamine in two distinct mouse models of autismImmunoblotting of TH and DAT in the striatum after intranasal delivery of vehicle (VEH) or dopamine (DA). a Western blots of striatal lysates from BTBR mice treated with VEH or DA. Increased TH expression was found after DA administration. b Western blots of striatal lysates from Fmr1-KO mice treated with VEH or DA. Reduced TH level was noticed after DA application. In both cases, DAT protein was unaltered by intranasal DA. TH: tyrosine hydroxylase; DAT: dopamine transporter. n = 5–6 mice/group. *p < 0.05, compared to VEHBack to article page