Fig. 1

The protein level of TMEM175 in neurons decreases after I/R injury. a Western blot analysis and quantification of the protein level of TMEM175 in ischemic penumbra (12 h vs. sham, ****p < 0.0001; 12 h vs. 48 h, *p = 0.0248). b Western blot analysis and quantification of the protein level of TMEM175 in cultured neurons exposed to OGD/R (3 h vs. control, *p = 0.0457; 3 h vs. 48 h, *p = 0.0192). c Western blot analysis and quantification of the protein level of LAMP2 in ischemic penumbra. d Western blot analysis and quantification of the protein level of LAMP2 in cultured neurons exposed to OGD/R. In (a–d), mean values for the sham group and the control group were normalized to 1.0