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Fig. 2 | Molecular Brain

Fig. 2

From: TMEM175 mediates Lysosomal function and participates in neuronal injury induced by cerebral ischemia-reperfusion

Fig. 2

TMEM175 overexpression alleviates brain injury in a rat MCAO/R model. a Transfection efficiency of TMEM175 overexpression plasmid in rat brains (MCAO/R vs. sham, *p = 0.0215; MCAO/R + Vector vs. MCAO/R + Over-TMEM175, **p = 0.0091; sham vs. sham + Over-TMEM175, **p = 0.0034). Mean values for the sham group were normalized to 1.0. b TTC staining. (Vector vs. Over-TMEM175, *p = 0.0126). c FJC staining showing the effects of TMEM175 intervention on neuronal degeneration (Vector vs. Over-TMEM175, ****p < 0.0001)

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Molecular Brain

ISSN: 1756-6606