Fig. 3
From: Metallothionein-3 as a multifunctional player in the control of cellular processes and diseases
Summary diagrams depicting MT3 effects on diseases. MT3 contributes to the normal progression of redox reaction, lysosomal biogenesis, autophagy, apoptosis, endocytosis, and cytoskeleton, which are all beneficial for cell survival. However, altered expression of MT3 in cortical astrocytes of null mice leads to various pathological conditions, such as Acute and chronic neuronal diseases, cancer, retinopathy, and diabetes. AD, Alzheimer disease; HD, Huntington disease; ALS, amyotrophic lateral sclerosis; AMD, age-related macular degeneration