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Fig. 1 | Molecular Brain

Fig. 1

From: Overexpression of Slit2 decreases neuronal excitotoxicity, accelerates glymphatic clearance, and improves cognition in a multiple microinfarcts model

Fig. 1

Overexpression of Slit2 improves spatial learning and memory deficits caused by cerebral microinfarct (CMI) induction. a Experimental timeline of BDA injection and Morris water maze (MWM) testing, Two-photon imaging and pathological analysis. b Latencies to the hidden platform (escape latencies) during training trials by wild type (WT) sham, WT cerebral microinfarct (MI), Slit2-Tg sham, and Slit2-Tg MI groups. c Swim paths during the probe trial. d Number of target area crossings and time spent in the target quadrant during the probe trial. Each dataset is expressed as mean ± SD. *P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.001; ****P ≤ 0.0001. n = 6 mice

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Molecular Brain

ISSN: 1756-6606