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Fig. 5 | Molecular Brain

Fig. 5

From: Overexpression of Slit2 decreases neuronal excitotoxicity, accelerates glymphatic clearance, and improves cognition in a multiple microinfarcts model

Fig. 5

Overexpression of Slit2 reduces peri-infarct neuronal loss and microglia/macrophage activation. a Immunofluorescence staining of neurons and microglia/macrophage (20×). b Comparison of microinfarct volumes between WT MI and Slit2-Tg MI groups. c Comparisons of neuron and microglia/macrophage numbers among WT sham, WT MI, Slit2-Tg sham, and Slit2-Tg MI groups (20×, 1 field/slice, 5 slices per mouse). Each dataset is expressed as mean ± SD. *P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.001; ****P ≤ 0.0001. n = 6 mice

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