Skip to main content
Fig. 1 | Molecular Brain

Fig. 1

From: Kappa opioid receptors in the central amygdala modulate spinal nociceptive processing through an action on amygdala CRF neurons

Fig. 1

Recording, drug administration and optical stimulation sites. a-d Coronal brain slices. Numbers next to diagrams indicate distance from bregma. a Location of tips of microdialysis probes in the CeA for drug application (n = 12 sites). b Location of tips of optical fibers for optogenetic stimulation of CRF-CeA neurons (n = 8 sites). c Confocal image of eYFP fluorescence in CRF neurons in the CeA following viral vector (rAAV5/EF1a-DIO-eNpHR3.0-eYFP) injection to express halorhodopsin (see Materials and Methods, Optogenetics). d Site of electrolytic lesions indicating recording sites in CeA. e Spinal cord slice showing recoding sites in the dorsal horn of lumbar segment L4. a-e Scale bars, 500 μm

Back to article page

Molecular Brain

ISSN: 1756-6606