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Fig. 4 | Molecular Brain

Fig. 4

From: Distinct role of 5′UTR sequences in dendritic trafficking of BDNF mRNA: additional mechanisms for the BDNF splice variants spatial code

Fig. 4

Predicted folding of exon 2 mRNA variants. a–c Predicted secondary structures using the RNAfold platform from the University of Vienna (https://rna.tbi.univie.ac.at/cgi-bin/RNAWebSuite/RNAfold.cgi) of BDNF mRNA 5′UTR splicing variants exon 2a (a), 2b (b) and 2c (c). The overall secondary structures of each exon are reported on the right. The insets on the left highlight a common region displaying a putative binding site for two clusters of RNA binding proteins: CPEB2/CPEB4, HNRNPC/CL1, HuR, TIA1 cluster (green curved line) and HNRNPA2/B1 cluster (orange straight line)

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Molecular Brain

ISSN: 1756-6606