Fig. 2

Microglial activation is reduced in Hv1^−/− mice after SCI. a Representative images showing time course of microglial activation (Iba1) in Hv1^−/− and WT mice after SCI (Scale: 200 µm). Insets show higher magnification images of single Iba1⁺ cell from the lower magnification image (Scale: 15 µm). b, c Bar graph denotes number and soma size of Iba1⁺ cells per field of view (fov) in ventral horn in sham, 1 d, 3 d and 7 d in both WT and Hv1^−/− mice. Data is represented as mean ± SEM. (*P < 0.05, **P < 0.01, ***P < 0.001, Student’s t-test, n = 3–5 per group)