Region | Group | Distance from bregma | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
3 mm | 2 mm | 1 mm | 0 | − 1 mm | − 2 mm | − 3 mm | − 5 mm | − 6 mm | ||
IC | Control |  | 2.44 ± 0.47 | 1.64 ± 0.17 | 1.49 ± 0.29 | 1.54 ± 0.32 | 1.31 ± 0.18 |  |  |  |
Torin1 |  | 1.25 ± 0.13** | 1.05 ± 0.12** | 1.04 ± 0.08 | 1.12 ± 0.12 | 1.04 ± 0.08 |  |  |  | |
XL388 |  | 1.27 ± 0.17** | 1.03 ± 0.09** | 0.98 ± 0.12 | 0.91 ± 0.04 | 0.83 ± 0.06 |  |  |  | |
S1HL | Control |  |  |  | 2.89 ± 0.45 | 2.68 ± 0.49 | 2.20 ± 0.25 |  |  |  |
Torin1 |  |  |  | 1.71 ± 0.16** | 1.78 ± 0.21** | 1.49 ± 0.13** |  |  |  | |
XL388 |  |  |  | 1.51 ± 0.14** | 1.45 ± 0.14** | 1.32 ± 0.12** |  |  |  | |
M1/2 | Control | 2.53 ± 10.37 | 2.85 ± 9.35 | 2.85 ± 0.41 | 2.34 ± 0.36 | 2.08 ± 0.39 | 1.68 ± 0.13 | 1.72 ± 0.18 |  |  |
Torin1 | 1.81 ± 0.19 | 1.86 ± 0.21** | 1.72 ± 0.21** | 1.66 ± 0.19 | 1.69 ± 0.23 | 1.47 ± 0.16 | 1.50 ± 0.20 |  |  | |
XL388 | 1.92 ± 0.16 | 1.95 ± 0.28* | 1.82 ± 0.18** | 1.69 ± 0.16 | 1.46 ± 0.13 | 1.39 ± 0.15 | 1.28 ± 0.10 |  |  | |
ACC | Control |  | 2.31 ± 0.23 | 1.96 ± 0.19 | 1.89 ± 0.36 | 2.11 ± 0.46 |  |  |  |  |
Torin1 |  | 1.93 ± 0.48** | 1.93 ± 0.48** | 1.91 ± 0.48 | 1.92 ± 0.47 |  |  |  |  | |
XL388 |  | 1.30 ± 0.12** | 1.26 ± 0.10** | 1.23 ± 0.08 | 1.20 ± 0.08 |  |  |  |  | |
V1/2 | Control |  |  |  |  |  |  |  | 1.49 ± 0.15 | 1.46 ± 0.15 |
Torin1 |  |  |  |  |  |  |  | 1.38 ± 0.07 | 1.42 ± 0.10 | |
XL388 |  |  |  |  |  |  |  | 1.33 ± 0.14 | 1.43 ± 0.17 |