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Fig. 2 | Molecular Brain

Fig. 2

From: Selective role of the translin/trax RNase complex in hippocampal synaptic plasticity

Fig. 2

Translin KO mice show no alterations in predominantly presynaptic forms of long-lasting LTP. a Theta-burst stimulation (15 bursts of four 100 Hz pulses delivered at 5 Hz for a total of 3 s) induced similar levels of long-lasting LTP in slices from translin KO mice (n = 5; 1 male, 4 females) or wildtype littermates (n = 5; 2 males, 3 females) (two-way repeated measures ANOVA, F(1,8) = 0.007, p = 0.94). b Slices from translin KO mice (n = 5; all females) and wildtype littermates (n = 6; 1 male, 5 females) displayed similar levels of forskolin (FSK)-induced long-lasting potentiation (two-way repeated-measures ANOVA, F(1,9) = 0.07, p = 0.79). Representative traces before (black) and after (red) stimulation are shown on top of each graph. Scale bars for traces 2 mV, 2 ms. ‘n’ refers to the number of mice used. Error bars reflect S.E.M

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