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Fig. 8 | Molecular Brain

Fig. 8

From: Protrudin-deficient mice manifest depression-like behavior with abnormalities in activity, attention, and cued fear-conditioning

Fig. 8

Spatial reference memory of protrudin-deficient mice assessed with the Barnes maze test. a–d Latency to reach the target hole (a) as well as the number of errors (b), distance traveled (c), and number of omission errors (d) before reaching the target hole during training sessions. e, f Time spent around each hole in probe trials conducted 1 day (e) and 28 days (f) after the last training session. All data are means ± SEM (WT mice, n = 22; PRT–/– mice, n = 15). P values for differences between genotypes were determined by two-way repeated-measures ANOVA (a–d) or Wilcoxon rank sum test (e, f). The results of all statistical analysis are provided in Additional file 1: Table S1

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