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Fig. 3 | Molecular Brain

Fig. 3

From: Chd8 mutation in oligodendrocytes alters microstructure and functional connectivity in the mouse brain

Fig. 3

Contralateral connectivity in Olig1-Cre/Chd8L+/F and control mice. a Correlation matrices derived from rsfMRI BOLD signal analysis for connections between left and right hemispheres of the cerebral cortex (n = 12 mice per genotype). MO motor cortex, SS somatosensory cortex, AUD auditory cortex, VIS visual cortex, ACA anterior cingulate cortex, PL prelimbic cortex, ILA infralimbic cortex, ORB orbitofrontal cortex, AI agranular insular cortex. b The t-value for significantly altered contralateral regional connectivity of Olig1-Cre/Chd8L+/F mice compared with Olig1-Cre/Chd8+/+ mice (FDR-adjusted P value of < 0.05). c Strength of the correlation (Fisher’s z-score) between the indicated brain regions of Olig1-Cre/Chd8L+/F and Olig1-Cre/Chd8+/+ mice (n = 12 mice per genotype). Data are means + SEM. P values were determined with Student’s t test. The results of rsfMRI processing without GSR are provided in Additional file 3: Fig. S2

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