Skip to main content
Fig. 1 | Molecular Brain

Fig. 1

From: Zonisamide can ameliorate the voltage-dependence alteration of the T-type calcium channel CaV3.1 caused by a mutation responsible for spinocerebellar ataxia

Fig. 1

Effect of ZNS on mutant CaV3.1. a Representative traces of T-type VDCC currents recorded from HEK293T cells expressing WT without ZNS (left), MT without ZNS (middle), or MT with 50 µM ZNS (right). WT is wild-type and MT is mutant CaV3.1. b Comparison of Ca2+ current density at a holding potential of − 30 mV. No significant difference was observed between WT without ZNS and each group (WT with 50 µM ZNS, p = 0.588; MT without ZNS, p = 0.355; MT with 50 µM ZNS, p = 0.816)

Back to article page