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Fig. 3 | Molecular Brain

Fig. 3

From: Zonisamide can ameliorate the voltage-dependence alteration of the T-type calcium channel CaV3.1 caused by a mutation responsible for spinocerebellar ataxia

Fig. 3

Effect of efonidipine on mutant CaV3.1. a Representative traces of T-type VDCC currents recorded from HEK293T cells expressing WT without efonidipine (left), MT without efonidipine (middle), or MT with 5 µM efonidipine (right). b Comparison of the Ca2+ current density at a holding potential of − 40 mV. No significant difference was observed between WT without efonidipine and each group (WT with 5 µM efonidipine, p = 0.727; MT without efonidipine, p = 0.585; MT with 5 µM efonidipine, p = 0.312)

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