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Fig. 4 | Molecular Brain

Fig. 4

From: CCL2 facilitates spinal synaptic transmission and pain via interaction with presynaptic CCR2 in spinal nociceptor terminals

Fig. 4

Ultrastructural preembedding double immunostaining showing the localization of CCR2 expression in the presynaptic terminal of the spinal cord. a–c Immunogold particles indicating that CCR2 immunoreactivity is mainly localized in the inside of the dendrites (yellow arrows), partly localized on the postsynaptic membrane (purple arrows), presynaptic membrane (pink arrows, a, c) and partly localized in presynaptic (red arrows). d Immunogold particles showing that CCR2 immunoreactivity is localized in glial filament (blue arrow). e, f Immunogold particles showing that CCR2 immunoreactivity is localized in the inside of the dendrites (yellow arrows) closing to synaptic vesicle (green arrows) and partly localized in presynaptic (red arrows). Den: dendrite, T: terminal, GF: glial filament. Scale bar = 0.5 μm

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Molecular Brain

ISSN: 1756-6606