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Table 2 Summary of exploratory behaviors in the open-field test

From: Global knockdown of glutamate decarboxylase 67 elicits emotional abnormality in mice

  Gad1+/+ Gad1tTA/STOP−tetO t values p values
Total distance (cm) 2434.4 ± 102.7 3495.0 ± 179.7 5.389  < 0.001
Total duration of movement (s) 166.8 ± 4.9 185.7 ± 5.5 2.235 0.036
Total number of movement episode 95.4 ± 2.1 86.7 ± 2.6 2.330 0.029
Moving speed (cm/s) 13.1 ± 0.3 17.8 ± 0.7 6.784  < 0.001
Distance per movement (cm) 23.4 ± 1.3 38.7 ± 3.1 5.380  < 0.001
Duration per movement (s) 1.8 ± 0.1 2.2 ± 0.1 3.295 0.003
Time spent in the wall side (s) 246.9 ± 5.5 271.6 ± 5.3 2.671 0.014
Time spent in the center region (s) 53.1 ± 5.5 28.4 ± 5.3 2.671 0.014
% Time spent in the center region 17.7 ± 1.8 9.5 ± 1.8 2.670 0.014
  1. Exploratory behaviors were measured for 5 min in the open-field in Dox-treated Gad1+/+ (n = 17) and Gad1tTA/STOP−tetO (n = 7) mice. Data represent the mean ± SE. A p value less than 0.05 was considered a significant difference (Student’s t-test)
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