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Table1 The associations between sex hormone traits and mental traits in males and females

From: Evaluating the genetic effects of sex hormone traits on the development of mental traits: a polygenic score analysis and gene-environment-wide interaction study in UK Biobank cohort

  

Number

Age ± Sd

Beta

P value

Total people

SHBG _ Frequency of alcohol consumption

388571

56.56 ± 8.07

0.0101

3.84 × 10–11

 

Total T _ Frequency of alcohol consumption

388571

56.56 ± 8.07

0.0067

1.59 × 10–5

Males

Total T _ Frequency of smoking

185464

56.51 ± 8.22

− 0.0108

2.07 × 10–6

 

SHBG_ Frequency of alcohol consumption

189153

56.84 ± 8.15

0.0090

8.18 × 10–5

 

Estradiol _ Frequency of alcohol consumption

189153

56.84 ± 8.15

0.0128

1.96 × 10–8

Females

Bioavailable T _ Fluid intelligence

86777

56.46 ± 8.06

− 0.0136

5.74 × 10–5

 

Total T _ Frequency of alcohol consumption

199167

56.29 ± 7.97

0.0102

4.55 × 10–6

  1. Bioavailable testosterone (Bioavailable T); sex hormone-binding globulin (SHBG); Total testosterone (Total T)