Fig. 3

Energy minimized theoretical complexes of histamine H3 receptor with histamine (a) and PEA-OXA (b). Protein is colored in tan, histamine in light blue and PEA-OXA in slate gray. Ligands and residues within 5 Å from the ligands are shown in stick representation. Oxygen, sulfur and nitrogen heteroatoms are colored in red, yellow and blue, respectively. H-bonds are represented as green springs