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Fig. 1 | Molecular Brain

Fig. 1

From: Pcdhβ deficiency affects hippocampal CA1 ensemble activity and contextual fear discrimination

Fig. 1

Pcdhβ deficiency reduces repetitive neuronal activity in the hippocampus. a Pcdhβ deletion. b Induction of CaMKII-G-CaMP7 by AAV and implantation of GRIN lens over the right hippocampal CA1 region. c Ca2+ imaging in home cage (pre) and square context (sq). d Schematic of the correlation matrix analysis. Representative images of correlation matrices for activation in Wt (e) and Δβ (f) mice. g Summation of correlation coefficients between sessions (n = 5 Wt mice, 4 Δβ mice). Data are means ± standard errors of the means (SEMs). **P < 0.01 (adjusted P-value from Bonferroni’s multiple-comparison test)

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