Epitranscriptomic profiling of N6-methyladenosine-related RNA methylation in rat cerebral cortex following traumatic brain injury

Table 1 The top 20 significantly changed m6A methylation peak based on p-value

mRNA	Chromosome	Peak region	Peak start	Peak end	Lg (p-value)	Log₂ (fold-change)	Up/Down
Sp4	6	3′ UTR	146,193,411	146,193,560	−434	−1.90	Down
Mycbp2	15	Exon	87,493,207	87,494,725	−434	−3.83	Down
Pias4	7	Exon	11,414,644	11,423,227	−8.36	−2.14	Down
Fbxo32	7	3′ UTR	98,065,124	98,067,070	−8.13	−1.43	Down
Crhbp	2	5′ UTR	25,152,370	25,153,284	−7.28	−1.61	Down
Kcnj11	1	3′ UTR	102,103,938	102,104,138	−7.15	−1.83	Down
Amer3	9	Exon	41,096,883	41,097,424	−7.00	−1.82	Down
Spg7	19	3′ UTR	55,913,654	55,913,954	−6.85	−2.99	Down
Slc2a13	7	5′ UTR	132,757,358	132,757,508	−6.62	−2.47	Down
Trpc6	8	Exon	6,872,050	6,872,448	−6.62	−1.50	Down
Slfn4	10	5′ UTR	70,428,465	70,428,814	−7.21	1.81	Up
Mdfic	4	3′ UTR	42,280,721	42,280,870	−6.79	4.17	Up
Prss35	8	3′ UTR	94,438,220	94,439,065	−6.27	1.05	Up
Ppp1r3b	16	3′ UTR	60,418,476	60,418,677	−6.18	3.14	Up
Nlgn3	X	Exon	71,221,689	71,222,484	−6.18	1.03	Up
Hcn1	2	Exon	50,495,344	50,499,750	−6.13	1.12	Up
Rps6kb1	10	5′ UTR	73,854,215	73,865,364	−6.08	1.49	Up
Gpkow	X	3′ UTR	15,638,954	15,640,719	−6.02	2.39	Up
Prelid3a	18	3′ UTR	63,213,663	63,215,734	−5.87	2.87	Up
Pprc1	1	Exon	265,818,641	265,818,890	−5.80	4.01	Up

ISSN: 1756-6606