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Fig. 4 | Molecular Brain

Fig. 4

From: Upregulation of Beta4 subunit of BKCa channels in the anterior cingulate cortex contributes to mechanical allodynia associated anxiety-like behaviors

Fig. 4

Decreased BKCa currents of ACC pyramidal neurons from mCCD rats. a, Voltage ranges from − 60 to + 40 mV with 10 mV increments, typical recordings of BKCa currents in pyramidal neurons from sham (left) and mCCD (right) rats, BKCa currents were isolated with paxilline (10 μM). b, The I-V relationship curves showed the differences in the ACC pyramidal neurons from mCCD (n = 12) and sham (n = 12) rats. c, BKCa current density at + 40 mV from voltage-clamp recordings of ACC pyramidal neurons from mCCD (n = 12) and sham (n = 12) rats. **p < 0.01 compared with that of sham group

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