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Table 3 Quantitative ultrastructural analysis of CA1 synapses

From: Double deletion of the active zone proteins CAST/ELKS in the mouse forebrain causes high mortality of newborn pups

 

Control

ELKS cKO

Synapse density (per 100 μm2)

37.3 ± 1.12

38.7 ± 1.23

Presynaptic terminal area (nm2)

0.177 ± 0.017

0.190 ± 0.017

Size of active zone (nm)

182.0 ± 3.22

180.3 ± 6.82

Docked synaptic vesicle (per 100 nm active zone)

1.64 ± 0.256

1.86 ± 0.203

  1. Images were obtained from the striatum radiatum of the hippocampal CA1 region. Data are presented as mean ± SEM, determined by the values from more than 100 synapses from each of 3 individual animals (control and ELKS cKO)