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Fig. 4 | Molecular Brain

Fig. 4

From: Scopoletin ameliorates anxiety-like behaviors in complete Freund’s adjuvant-induced mouse model

Fig. 4

SP improved changes in glutamate and GABAA receptor expression in the BLA of CFA-injected mice. a Representative western blot analysis of GluA1, GluN2A, GluN2B, and PSD95 expression. SP treatment reversed the increased expression of GluA1 (b) and PSD95 (e), but had no apparent effect on GluN2A (c) and GluN2B (d) normalized to β-actin. f Representative western blot analysis of GABAA α2 and GABAA γ2 expression. SP treatment significantly reversed the decreased expression of GABAA α2 (g) and GABAA γ2 (h) normalized to β-actin. n = 6 mice from three independent experiments; **p < 0.01 versus control group; #p < 0.05, ##p < 0.01 versus vehicle group

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