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Fig. 2 | Molecular Brain

Fig. 2

From: Nicotinamide attenuates the decrease in dendritic spine density in hippocampal primary neurons from 5xFAD mice, an Alzheimer’s disease animal model

Fig. 2

Relative abundance of metabolites in the hippocampus in 5xFAD mice at each age. a nicotinamide, b AMP, c LysoPC (16:0), d LysoPC (18:0), and e LysoPE (16:0). Data are shown as means ± SEM of at least 3 independent experiments; 6 M-WT (n = 9), 6 M-5xFAD (n = 9), 8 M-WT (n = 6), 8 M-5xFAD (n = 7), 12 M-WT (n = 9), and 12 M-5xFAD (n = 8). *q < 0.05 compared with age-matched WT mice. AMP, adenosine monophosphate; LysoPC, lysophosphatidylcholine; LysoPE, lysophosphatidylethanolamine

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