From: Nicotinamide attenuates the decrease in dendritic spine density in hippocampal primary neurons from 5xFAD mice, an Alzheimer’s disease animal model
Age (month)
Genotype
HPC weight (mg)
N
Mean ± SD
(min-max)
6
WT
20.5 ± 3.4
9
(15.0–25.6)
5xFAD
20.3 ± 5.4
(14.5–28.6)
8
21.1 ± 2.7
(17.8–25.7)
24.4 ± 3.2
7
(20.4–29.2)
12
19.7 ± 4.2
(10.0–24.9)
18.4 ± 2.8
(13.1–21.8)