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Table 1 The number of male mice and tissue weights. The mice were classified into 6 groups based on age (6, 8, and 12 months). HPC, hippocampus; SD, standard deviation

From: Nicotinamide attenuates the decrease in dendritic spine density in hippocampal primary neurons from 5xFAD mice, an Alzheimer’s disease animal model

Age (month)

Genotype

HPC weight (mg)

N

Mean ± SD

(min-max)

6

WT

20.5 ± 3.4

9

 

(15.0–25.6)

 

5xFAD

20.3 ± 5.4

9

 

(14.5–28.6)

 

8

WT

21.1 ± 2.7

6

 

(17.8–25.7)

 

5xFAD

24.4 ± 3.2

7

 

(20.4–29.2)

 

12

WT

19.7 ± 4.2

9

 

(10.0–24.9)

 

5xFAD

18.4 ± 2.8

8

 

(13.1–21.8)