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Fig. 3 | Molecular Brain

Fig. 3

From: Conditional Pten knockout in parvalbumin- or somatostatin-positive neurons sufficiently leads to autism-related behavioral phenotypes

Fig. 3

Increased self-grooming in PV-Pten-KO and Sst-Pten-KO mice. a The number of self-grooming bouts increased in PV-Pten-KO mice (WT: n = 24, Het: n = 17, KO: n = 25; F(2,63) = 4.758, p = 0.012, one-way ANOVA; KO vs. WT: p = 0.015, Tukey’s post hoc test). b The total time of self-grooming increased in PV-Pten-KO mice (WT: n = 24, Het: n = 17, KO: n = 25; F(2,63) = 3.635, p = 0.032, one-way ANOVA; KO vs. WT: p = 0.036, Tukey’s post hoc test). c The number of self-grooming bouts increased in Sst-Pten-KO mice (WT: n = 12, Het: n = 16, KO: n = 18; F(2,43) = 4.025, p = 0.0250, one-way ANOVA; KO vs. WT: p = 0.0199, Tukey’s post hoc test). d The total time of self-grooming increased in Sst-Pten-KO mice (WT: n = 12, Het: n = 16, KO: n = 18; F(2,43) = 6.249, p = 0.004, one-way ANOVA; KO vs. WT: p = 0.003, Tukey’s post hoc test). Circles represent data from individual animals, and bar graphs indicate mean + SEM. *: statistically significant

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Molecular Brain

ISSN: 1756-6606