Fig. 4

Improvement of working memory performance of GD mice in the eight-arm radial maze test. Spatial learning was tested in the eight-arm radial maze test on 4 months WT (□; n = 9) and GD (■; n = 12) mice. aThe number of different arm choices in the first eight entries, b the number of revisiting errors, c the latency to acquire eight pellets and d and the distance traveled, are presented. e–g Results of the eight-arm radial maze test with delays of 3, 120, 300 s. The number of different arm choices in the first eight entries (e), the number of revisiting errors (f) and latency (g) were presented. One WT mouse died after trials. The p-values indicate genotype effect in two-way repeated measures ANOVA (a–g) or one-way ANOVA (e–g, for each delay time). Values are means ± SEM