Fig. 2From: iTRAQ-based proteomic profiling reveals protein alterations after traumatic brain injury and supports thyroxine as a potential treatmentGeneral proteomic outcomes. a Principal component analysis indicated a near complete separation of proteins in the TBI (blue) and sham (yellow) groups. b 125 proteins were upregulated, and 21 proteins were downregulated. c Volcano plot showed differentially expressed proteins. The red and green dots indicate significantly upregulated and downregulated proteins, respectively. d Hierarchical cluster analysis. Red indicates upregulation, and green indicates downregulation. The dendrograms represent the classification of proteins. The number in the color scale indicates z-scoreBack to article page