Fig. 1
From: Ethosuximide inhibits acute histamine- and chloroquine-induced scratching behavior in mice
Ethosuximide inhibits acute itch responses induced by histamine. Dose-dependent inhibition of the total time scratching the nape in (a, c) male or (b, d) female mice by ethosuximide when delivered (a, b) systemically (10.0–30.0 mg/kg, i.p.) before histamine treatment, or (c, d) when co-delivered (10.0–100.0 μg/co-injected) with histamine. Each bar represents the mean ± S.E.M. and is representative of two or three experimental runs. Numbers shown in the bars reflect numbers of mice. One-way ANOVA reveals significant differences