Fig. 3
From: Caveolin-1 deficiency impairs synaptic transmission in hippocampal neurons
Synaptic vesicle exocytosis rate is significantly decreased in Cav1-KD neurons. a Representative normalized traces of Physin-pH exocytosis from Control (black) and Cav1-KD (red) neurons. b Quantification of exocytosis, expressed as mean values of time constants (τ) ± SEM, in Control (τexo, 34.61 ± 4.23; n = 12 cells) and Cav1-KD (τexo, 58.12 ± 5.84; n = 14 cells) neurons. c Representative traces of Physin-pH responses to 2000 APs at 10 Hz in the presence of bafilomycin A1 (BAF) in control and Cav1-KD neurons. d Quantification of recycling vesicle pool size expressed as means ± SEMs in Control (0.62 ± 0.04; n = 12 cells) and Cav1-KD (0.45 ± 0.04; n = 14 cells) neurons (**p < 0.01)