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Fig. 1 | Molecular Brain

Fig. 1

From: Developmental up-regulation of NMDA receptors in the prefrontal cortex and hippocampus of mGlu5 receptor knock-out mice

Fig. 1

Influence of genetic deletion of mGlu5 receptors on the expression of interneuron-related genes in the prefrontal cortex and hippocampus across postnatal development. mRNA levels encoding interneuron-related proteins in the prefrontal cortex and hippocampus at PND9 -21 and -75 are shown in a and b, respectively. Values are means ± S.E.M. of 5–9 mice per group. * p< 0.05 vs. the corresponding values of wild-type littermates (Student’s t-test). a PND9: Pvalb, t10 = 2.3; Reln, t10 = 5.6; Vip t10 = 5.6; PND21: GAD1, t11 = 4; Pvalb, t11 = 3.1; PND75: GAD2, t5 = 2.8, Pvalb, t5 = 3.2, Vip, t5 = 2.6. b PND9: Pvalb, t8 = 11.1; Reln, t7 = 3.5; PND21: Vip, t9 = 2.2; PND75: SSt, t6 = 6.2

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Molecular Brain

ISSN: 1756-6606